Sentence examples for better define the effects from inspiring English sources

To better define the effects of miR-17 and miR-20a on gene expression we conducted knock-in (with synthetic miRNA) and knock-down (with LNA modified anitmiRs) experiments using Jurkat cells (performed in triplicate).

Therefore, future studies should better define the effects of phthalate exposure in the offspring of animals exposed in utero and determine whether or not the LOAEL decreases in subsequent generations.

To better define the effects of MIF knock down in melanoma cell lines, particularly their decreased proliferative capacity, the ability of cells to enter the S-phase of the cell cycle was measured using the Click-iT™ EdU flow cytometry assay.

In the present study, we analyzed the genomic and proteomic expression of HCC cells transfected with HBx with C-terminus mutations, in order to better define the effects of the HBx mutants in the development and procession of HCC associated with HBV infection.

To better define the effects of hypoxia in the synovial microenvironment, we studied the response of fibroblast-like synoviocytes (FLS) to hypoxic stimulation using the gene expression microarray, quantitative RT-PCR, and matrix-assisted laser desorption-time of flight mass spectrometry.

Several scales have been combined in stroke trials to derive a global statistic to better define the effect of acute interventions, although this composite statistic is not clinically tenable.

Finally, a statistical principal component analysis (PCA) was performed and the 2-dimensional graph (2D-plot) was used to better define the effect of supplementation with argan oil on physiological and oxidative stress parameters (Fig. 4).

To better define the effect of Foxc1 deletion on pre-natal cerebellar development, we assessed cerebellar morphology at e13.5, e15.5 and e17.5.

To better define the effect of the methyl groups normally found on dT residues in DNA on Fe·BLM-mediated DNA cleavage, we also compared the cleavage of DNA 9 and DNA 9-2dU at lower temperatures, where Fe·BLM cleaves B-form DNA less quickly, presumably reflecting the presence of a more compact DNA structure.

We sought to investigate whether analysis of midazolam plasma concentrations in combination with electroencephalography (EEG) will better define the effect of critical illness on the pharmacokinetics and clinical response to midazolam, while providing a method to assess the adequacy of sedation thereby minimizing the risks associated with prolonged or over-sedation.

A great deal of scientific data have been collected over the years to better define the toxic effects of Cd in the primary target organs.