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They are used nonetheless, because no better datasets are available.
Some limitations of the evidence may be overcome with better datasets and modeling approaches.
In order to improve the modelling further one key research need is for more and better datasets on weathering and the factors that control it.
The paper concludes by discussing some implications given future economic trends and advocates that better datasets from developing and newly developed countries are required for urban planning in developing countries.
We conclude that comparing methods indeed helps to better estimate how good the methods are, to improve the algorithms, to build better datasets and to build a comparison methodology.
While sequencing of multiple samples from the same tumor (Gerlinger et al., 2012; Newburger et al., 2013; Salari et al., 2013) or single-cell sequencing (Hou et al., 2012; Navin et al., 2011; Xu et al., 2012) might eventually provide even better datasets to assess intra-tumor heterogeneity, technical considerations have limited their applicability utility thus far.
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A better dataset at 2.3 Å resolution was later collected on the native P21 crystal and used for final refinement.
"There is no better dataset to prove this concept, because nobody is scrutinized more than professional athletes," says Smith. "But we believe this is the optimization of humans, whether you're a firefighter or you work at Google".
Extending monitoring programs to include flora and fauna results in a better dataset of ecosystem status, but also increases the complexity in interpreting whether the status is good or poor.
An even better dataset would have included all hospitalized patients, but a dataset including all necessary variables was not available at the time of analysis.
The unheated measurements thus provided a better dataset for machine learning and we reasoned that they would increase the diversity of designs of active proteinase K variants.
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