Sentence examples for beta chains of the from inspiring English sources

Polymorphisms in the DR beta chains of the Class II HLA molecule specify peptide-binding affinities.

A genetic analysis was performed to pinpoint a possible mutation in the gene coding the alpha and beta chains of the GM-CSF receptor (CSF2RA and CSF2RB).

Therefore, the genes encoding the alpha and beta chains of the GM-CSF receptor, and not those encoding SP or ABCA3, have been investigated.

Interestingly, we did find structural homology of PLIN5 with the alpha and beta chains of the mitochondrial protein ATP synthase (PropSearch) (Hobohm and Sander 1995), providing additional support for structural characteristics in the PLIN5 sequence that could determine mitochondrial localization.

The underlying cause was thought to be a dysfunction of the receptor of the granulocyte-macrophage colony-stimulating factor, however, a mutation in the genes encoding the alpha and beta chains of this receptor has not been found.

We focused on integrin β3 (Ithe), the beta chain of the integrin αIIbβ3 heterodimer and recapitulated a known pathway as a model.

In three independent experiments, band 1 corresponded to the beta chain of the non-erythroid spectrin isoform 2 while bands 2 and 3 to seven different isoforms of the alpha chain of the non-erythroid spectrin.

A single dominant and highly polymorphic DRB locus encoding the beta chain of the MHC class II DR heterodimer has been described in domestic sheep (Ovis aries, Ovar-DRB1), [6], [7] and cattle BoLA-DRB33, [9], [9].

Interestingly, v-Src has been reported to directly phosphorylate the beta chain of the IGF-1 receptor at the corresponding autophosphorylation sites in rat fibroblasts with subsequent activation of IGF-1R kinase, and IGF-1R is required for v-Src transforming activity [40].

The region V beta (VβV) has been identified as the binding position for superantigens and is located in the variable part of the beta chain of the TCR.

Another interesting feature observed with all four growth factors was marked downregulation of the beta chain of the interleukin 2 receptor (IL2RB).