Sentence examples for beta cells that contribute from inspiring English sources
The incidence of and susceptibility to Type 2 diabetes increases with age, but the underlying mechanism(s) within beta cells that contribute to this increased susceptibility have not been fully elucidated.
The latter encompass monocytes, macrophages, and dendritic cells that contribute not only to islet inflammation and apoptosis but also to the loss of peripheral tolerance to beta cells antigens.
CONCLUSION: The low levels of TGF-beta(1) in Ad-AST treatment promote apoptosis of macrophages and provide an environment that is more conducive to the proliferation or infiltration of cells that contribute to healthy vessels.
It can thus be concluded that Pdx1 expression declines with age in mouse beta cells, that this contributes to reduced beta cell function, and that beta cell function is particularly affected by reduced pdx1 levels with age.
Similarly, cells with a mature gene expression profile only form during the second wave, while the early cells do not contribute to the later bulk of mature beta cells that produce insulin at high levels [ 3].
The groups from the Joslin Clinic and Washington University say the cells derived from a few beta cells that had survived the immune system onslaught.
In addition to regulating beta-cell functions that contribute tumor progression, PERK may also regulate functions in other cell types including the vascular endothelial cells that comprise the tumor macroenvironment.
The beta cell surface proteins that contribute to type 1 diabetes are likely to be very different from those involved in type 2 diabetes.
Altogether, our data support the idea that G7e and Fignl1 should be considered as genes that contribute to the cell cycle of beta cells; Fignl1 also seems to control cell survival.
They found that TGF-beta and interleukin-8 are specific tumor-secreted factors that contribute to the stem cells' eventual change in phenotype to myofibroblasts.
There is an ongoing debate whether these cells originate from beta-cells that turn-off maturation markers due to de-differentiation51, or whether the immature beta-cells represent newly differentiated beta-cells52.
