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Even within the best understood model of regulation of midline crossing, the Slit/Robo/Comm system, there is a consistent number of pleiomorphisms in the way the regulation is achieved: in the genome of many insects at least three Robo receptors are present; at least two are known to contribute to crossing in Drosophila.
Acetaminophen-induced liver damage is perhaps the best understood model of drug-induced liver injury.
AHL-mediated quorum sensing is the most widely studied and best understood model of cell-to-cell communication in Gram-negative bacteregulatingting various phenotypes.
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Ernest Drucker's "A Plague of Prisons: The Epidemiology of Mass Incarceration in America" makes the case that talk of an epidemic of imprisonment is more than a metaphor, and that what we are enduring is really best understood through the model of a classic runaway plague rather than as the consequence of rational decisions.
On the Classical view, the cognitive mind is best understood on the model of a digital computer that (i) uses symbolic representations that have a combinatorial syntax and semantics, and (ii) manipulates these representations following structure-sensitive processing rules.
Aristotle claims that perception is best
It is best understood as a unique model of how to build a short-lived community.
While the molecular control of auxin is best understood in the model plant Arabidopsis, which bears dry dehiscent fruit, there has been a substantial body of work in fleshy fruit species.
Molecular mechanisms underlying the asymmetric division of progenitor cells are best understood in invertebrate model organisms, such as Drosophila and Caenorhabditis elegans (Knoblich 2008).
T7 is one of the best understood of the tailed phages from molecular and physiology perspectives.
miRNAs are the best understood class of sRNAs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com