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The phrase "best to define" is correct and usable in written English
It can be used when suggesting that a particular definition or explanation is the most appropriate or effective. Example: "In order to clarify our discussion, it is best to define the key terms we are using."
Exact(51)
We will do our best to define human free will.
Do your best to define the least amount of notation and terminology necessary to state your main theorem(s).
For scientists who want to be active on social media, it is best to define and maintain a focus from the outset, he advised.
In particular, it is often unclear how best to define the population among which a specified number of legislative seats are to be apportioned.
So while there will be plenty of pomp and pageantry this week — Obama doing his best to define himself and, by extension, John McCain — the news will consist of what happens that wasn't supposed to happen.
But, of course, French politics have always been inseparable from French culture, and Sarkozy did his best to define his sense of culture in purely populist political terms: "A politician who doesn't watch TV can't know the French".
Similar(9)
Is the best way to define it simply the following?
Perhaps the best way to define a leisure suit is to say what it is not.
Officials are also wrestling with the best way to define Trealy's meats, smiles Swift.
Since then, even its best opportunities to define one have come and gone.
I don't think that Chuck, being from New York, is the best person to define what mainstream America is.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com