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The best specificities found with UrgIndex-hospitalisations series (92.9% and 85.8%) were associated with too long mean timeliness (respectively 5.5 and 5.0 days) for having any interest in early outbreak detection at the regional level.
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The best specificity and positive predictive value was for this last test with a cut-off point of 140 mg/dl in the second hour.
The 24-hour urine vanillylmandelic acid and norepinephrine measurements had the best sensitivity (97%), while the vanillylmandelic acid and homovanillic acid measurements had the best specificity (91%).
Of putative specific markers for diffuse malignant mesothelioma, nuclear staining with Zymed polyclonal calretinin antibody has shown the best specificity to date for epithelial diffuse malignant mesothelioma versus adenocarcinoma.
Also from the meta-analysis, regarding superior labral anterior to posterior (SLAP) tears, the test with the best sensitivity (52%) was the relocation test; the test with the best specificity (95%) was Yergason's test; and the test with the best positive likelihood ratio (2.81) was the compression-rotation test.
The detection of more than 3 positive chest quadrants upon lung ultrasound examination showed the best specificity (70%) and sensitivity (100%) for predicting an EVLW index >10 ml/kg ABW (area under ROC curve: 0.894; 95% CI 0.668 0.987, p < 0.0001, see Fig. 3).
The best specificity among groups of three syndromes was found for the group "Hyperthermia-Hyponatremia-Dehydration" (Table S1).
The algorithm had almost equal sensitivity for values <3, with the best specificity and accuracy obtained when the inflation rate was 1.5.
Antibody batches with the best specificity were purified.
The best LAP possesses the highest sensitivity (>50% expression) and the best specificity (<0.1% background).
In conclusion, FISH had best sensitivity (74.3%) whereas cytology had best specificity (75.5%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com