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Chondrocytes may provide the best source of cells for cartilage engineering.
Since most of the XO embryos die during the first trimester [4], HESCs, that differentiate into various embryonic cells, can be the best source of cells for studying the reasons for the early lethality in XO embryos.
Among the various sources of cells tested to date, fetal dopaminergic progenitors derived from the developing ventral mesencephalon (VM) remain the best source of cells identified to date.
The best source of cells to search for the HS-inducing epi-marks predicted by our model will be hESCs, as well as more committed stem cell lineages leading to the brain.
Thus, these meta-analyses demonstrated the feasibility of cell-based therapy, but there are some discrepancies in their findings and those of individual clinical trials regarding the best source of cells and the best route of delivery.
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In spite of this evidence, the definition of the conditions for a successful treatment (the best source of stem cells, their optimal concentration, the best route of delivery, the degree of differentiation, etc)., as well as the mechanisms by which stem cells may exert their protective action are still largely unresolved.
As biomarker research using ncRNAs is still in its infancy, there is no consensus yet on the best source of blood cells for the study of disease.
Finally, to approach to the best source of MSCs for transplantation we characterized cells isolated from mice 90 days after diabetes induction (diabetic) and compared them with MSCs obtained from age-matched healthy mice (normal).
In this case, the whole tumor cell represents the best source of immunizing antigens without knowledge of any specific antigen targets.
Therefore, the best source of supplemental LCPUFAs may be oil from single-cell algae and microscopic fungi, which contains adequate amounts of DHA and ArA.
Although the whole tumor cell vaccine can provide the best source of immunizing antigens, there is still a limitation that most tumors are not naturally immunogenic.
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