Sentence examples for best small molecule from inspiring English sources

Then, we collect the 100 best small molecule records with their respective database pathways and present these in CellFateScout.

This induction ratio represents over an order of magnitude improvement over the next best small molecule inducible system in PCC 7002 but is an order of magnitude lower than P trc in E. coli.

Inspired by BAA, one of the best small-molecule PAD4 substrates, the Thompson group installed reactive electrophilic fluoroacetamidine or chloroacetamidine warheads onto the BAA scaffold.

At the time when Wüthrich began his research, NMR worked best on small molecules.

The safety of poly(D,L-lactide)- b-polyethylene glycol-methoxy mPEG- b-PDLLA) mPEglycol-methoxy mPEG-ymeric micelles makes them one of the best delivery systems for small molecule anti-cancer drugs [ 31- 34].

In general, TFTRs are best known to bind small molecule ligands to control divergently oriented efflux pumps and, in addition to E. coli TetR, there are several good model systems including Staphylococcus aureus QacR [ 3].

Aptamers, or nucleic acid ligands, have gained clinical interest over the past 20 years due to their unique characteristics, which are a combination of the best facets of small molecules and antibodies.

Arguably the best cleavage agent for accurately mapping small molecule binding sites on DNA is the hydroxyl radical.

Computational docking is the core process of computer-aided drug design (CADD); it aims at predicting the best orientation and conformation of a small molecule (drug ligand) when bound to a target large receptor molecule (protein) in order to form a stable complex molecule.

The high tolerability of PARP1 for small molecules appended to 2H-phthalazin-1-one resulted in a number of high affinity binders in our small molecule library, the best representative of which, [124/131I]-I2-PARPi, was tested as a PET and SPECT tracer.

Central to this methodology is the notion of computational docking which is the process of predicting the best pose (orientation + conformation) of a small molecule (drug candidate) when bound to a target larger receptor molecule (protein) in order to form a stable complex molecule.