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The challenge with AIDS was working out which of dozens of biological markers had the best predictive value.
Serum myoglobin has clearly the best predictive value.
The total score has the best predictive value about full-scale IQ on WISC-III.
An area exceeding 80 mm2 had the best predictive value (sensitivity = 0.71, specificity = 0.67) with a 5.1 times increased risk (odds ratio = 5.1, CI 95% 1.45 to 18.05, p = 0.01) of recurrence.
ASA classification is the best predictive value for overall mortality.
Thrombin generation appears to have the best predictive value in the reversal of NOAC's anticoagulant effect.
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IPCL was the best PK parameter for predicting renal toxicity, showing the best predictive values.
This result comes from the marginal cost analysis of the equations with best predictive values.
Using ROC analysis, IL-6 (AUC 0.836, sensitivity 78.6%, specificity 75.9% for cut off 184 pg/mL) as well as C-reactive protein (AUC 0.804, sensitivity 71.4%, specificity 75.9% for cut-off 15.25 mg/dL) showed the best predictive values for positive SF results.
Obviously, the studies which provide the best predictive values have included almost exclusively patients with sepsis on admittance [ 7, 13].
They found the best predictive values for MT were provided by hemoglobin and the Quick value (AUC 0.87 for both parameters).
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