Sentence examples for best potency from inspiring English sources

Substitutions of aryl group at C-3 positions had a significant impact on the antitumor activities, and 3-Br substitution produced the best potency.

Substitution of the chromone moiety at the 6-position has a significant impact to the inhibitory activity, in particular a carboxylic acid group, produced the best potency.

The heptyl carbamate of 5-deoxo-3-hydroxyevodiamine (11c) shows the best potency with an IC50 value of 77 nM and very good selectivity over AChE.

We conclude that combinatorial approaches have the best potency to accomplish the most significant tumor destruction but further research is required to optimize such approaches.

Substitutions of aryl group at C-4 position had a significant impact on the antitumor activities, and 4-OH substitution produced the best potency.

Structure activity relationships (SARs) and docking studies indicated that aryl urea scaffolds had a significant impact on the antitumor activities, and aryl pyridine urea scaffolds produced the best potency.

The best analogs displayed better potency (IC50) than PTX and high selectivity for pjDHFR versus hDHFR, with 4 exhibiting a selectivity for pjDHFR of 24-fold.

Accordingly, PET/MRI holds the best potential to assess the potency or efficacy of tumor-suppressing treatments at preclinical and clinical levels [79].

Compound 31d showed best biochemical potency (Ki) of 6.7 μM.

The hybrid with a hexamethylene linker chain showed the best inhibitory potency.

The results obtained are significant and showing the best disintegrating potency on GBC fibrils with gemini surfactant.