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Therefore, the best possible values for k in (34) is that k min = ( 2 − 3 ) ( 3 + 2 2 ).
Calibration was performed during the running of the experiment: it was feasible to use an approach that found the best possible values for each parameter, for the best accuracy.
The aim of employing PSO algorithm in this study, is to find the best possible values for A, B and C parameters in Equation 2 which leads to have a more accurate DNA sensor model with better I-V characteristic.
These simulations are themselves subject to noise, and there is no guarantee that the best values we found are the best possible values.
We employed a box bounded global mixed-integer optimization algorithm [11] to determine best possible values for the RQA parameters m, τ, rmax, and lmin with respect to an optimal prediction probability pk for the 'awake' state using a training procedure.
Optimum cut-off points for SEAG, ALBR and FLDH were computed by using the statistical software StatsDirect (www.statsdirect.com) taking the best possible values for sensitivity and 1-specificity on the ROC plot.
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