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The best overall correlation (0.94) was obtained with 50 multiple imputations, a cross-section on the cell type and the possibility to apply a different model of the time effect for each cell type using a second order polynomial on the raw (untransformed) data.
The best overall correlation coefficient is 0.026 when ECFP4 and Pearson of landmark genes are used.
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The proposed models provided the best overall correlations.
Subject b05 reveals many of the features best, although the overall correlation between the gray-scale maps is not optimal (see parameter r1 in Table 1).
Phenology, as measured by Budburst, was the best overall predictor of gall abundance/shoot, with significant correlations for eight gall types (Table 3, Fig. 4C).
The number of sequences per group (Additional file 8: Figure S1) appears to be the best overall variable to detect groups likely to spend more time to be computed (correlation values between 0.40 and 0.54).
While the overall correlation between reaction flux and gene expression is moderate at best [ 34], increased expression of all genes participating in a particular pathway can be considered a good indication of increased flux [ 68].
By the time of their derivation, SFCscore functions were the best-performing scoring functions tested on large heterogeneous data sets, but the overall correlation was still not within the desired range.
For each model, for each arm, box plots of best overall response according to FISH score were also constructed and assessed visually to determine whether a clear correlation was apparent between tumor response and EGFR copy number.
For tumor-based IHC evaluations of resistance and mechanistic markers, no correlation was made between marker positivity and clinical outcomes for patients who had a best overall response of PR in this study.
While no penalty performed best overall, penalizing the variance among the estimated canonical eigenvalues on the logarithmic scale or shrinking the genetic towards the phenotypic correlation matrix appeared most advantageous.
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