Sentence examples for best mouse models for from inspiring English sources
Right now, the best mouse model for type 1 diabetes and actually one of the best mouse models for any human disease, is the nonobese diabetic (NOD) strain of mice.
To date, two of the best mouse models for human MKS are those carrying mutations in the Mks1 gene.
However, aged female mdx mice are by far the best mouse models for studying Duchenne dilated cardiomyopathy because they are genetically and phenotypically identical to affected humans (Bostick et al., 2010; Bostick et al., 2008b).
We have spent 10 years in the Animal Models of Diabetic Complications Consortium [AMDCC] trying to identify the best mouse model for diabetic kidney disease.
Taken together, these results support the notion that better- or best-fit mouse models for human studies can be identified by applying genome-scale comparison of gene expression patterns.
To test this hypothesis, we investigated whether comparison of global expression patterns of orthologous genes in human and mouse HCCs would identify similar and dissimilar tumor phenotypes, and thus allow the identification of the best-fit mouse models for human HCC.
The IFNα/βBP has been shown to contribute to poxvirus pathogenesis in VACV infections (18, 19), and more recently this has been confirmed using the mousepox model, considered the best surrogate mouse model for human smallpox.
Among others, extraction of up- or down-regulated genes specifically in K19-Wnt1/C2mE K19-Wnt1/C2mEmE respectively inferred that K19-Wnt1/C2mE mice world provide best-fit mouse model for intestinal-type gastric tumors.
To the best of our knowledge, this is the first study of mouse models for social disinhibition.
