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Consequently, the four single, as well as the four matched, Q matrix models were evaluated by using the DINA model for selecting the best fitting model, by using a diverse set of fit indices (Table 4).

The GTR + Γ [ 44] model was selected as the best fitting model by the hLRTs [see Additional file 1: Table S4].

The performance of the calibration was assessed by evaluating Spearman correlations, SEs of prediction, and mean squared errors between observed compared with predicted GDD means in the validation data set with the best fitting model by these metrics across food groups presented.

We chose a 5-year lag for our ELR analysis because a 5-year lag was reported to provide the best fitting model by two of the three studies (Garshick et al. 2012; Silverman et al. 2012; Steenland et al. 1998).

We used the likelihood ratio test to identify best fitting models by forward selection and confirmed by backwards elimination, with a nominal P-value of 0.05 as a threshold, and to test the null hypothesis that there is no association between a set of predictive features and risks for relatives.

We explored a number of trajectory models with the best fitting model selected by the Bayesian Information Criterion BICC) and the fit further assessed by ensuring the posterior probability of group membership for all participants exceeded 70%.

The analyses in this article are based on the best fitting model found by Antoniou et al (2002).

For all partitions the GTR+I+G was determined as the best-fitting model by MrAIC.

Finally, when we found evidence of heteroskedasticity, we extended the best-fitting model by allowing the variance to follow a first-order autoregressive conditional heteroskedastic process (17).

We used BEAST v1.6 [ 119, 120] to estimate the divergence dates within our 8 supermatrices, by applying the best fitting model, as estimated by MODELTEST 2.0 to each of the partitions.

Model 3 (2-factor solution that did not include the GD: Mixed symptoms scale) was judged to be the best fitting model as evidenced by acceptable normed Chi Square, good fit indices and the lowest AIC of any tested model.