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The framework attempts to balance: our experiences as working scientists and technologists, our best current understanding of the social processes of knowledge production, and the possibility of mathematical analyses.
If holding responsible is best understood as resting on an independent judgment about being responsible, then it is legitimate to inquire whether such underlying judgments and their associated outward expressions can be justified, as a whole, in the face of our best current understanding of the world, e.g., in the face of evidence that our world is possibly deterministic.
Facts for Life represents the best current understanding of science, policy and practice.
Dietary recommendations are intended to inform the public about the best current understanding of food choices to support good nutrition and good health, but may also be used to provide nutritionally balanced meals for individuals who cannot make autonomous, informed decisions about food choices.
The best current understanding suggests that in the setting of volume expansion or pressure overload, the resulting wall stress initiates synthesis of pre-pro-brain natriuretic peptide (BNP) in the ventricular myocardium, although some have questioned the correlation between individual changes in blood volumes and natriuretic peptide levels.
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A new philosophy of history will grapple with issues of social explanation that have been so important for the current generation of social-science historians and will incorporate the best current understandings of the philosophy of social science about social ontology and explanation.
Yet this results largely in broad classifications of tumors, which to the best of our current understanding may act quite differently on a biological level.
The question is which of the four most likely adaptive functions best fits our current understanding of ABP: immunity, reproduction, chemosensation or toxin metabolism?
Given the apparent lack of autocorrelation of substitution rates, together with the intrinsic topological uncertainty in the Neornithes tree, the analyses in BEAST best reflect our current understanding of early avian evolution.
The increase in inflammatory response seen in recent DF patients may be due to a change in pathogenicity of the virus, although any viral mutation would be speculative at best with our current understanding of the disease.
Having identified the "best" option given our current understanding of the problem, we must then incorporate the residual uncertainty surrounding this choice into the evaluation, explore the level of confidence in the decision, and identify what future research is needed (4 ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com