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Exact(48)
The IC50's of the best compounds were superior to their parent compound febrifugine.
The best compounds from the series displayed low nanomolar inhibitory activity and are selective versus PDE4.
The best compounds on both series show IC50 values between 3 and 8 nM.
So in Nick's lab at the pharmaceutical company, he began screening for agents that worked on C.M.L. He'd send me his best compounds.
The two best compounds of the series tightly bind the telomeric quadruplex with a 2 1 drug/DNA stoichiometry.
The best compounds in this series overcome all types of resistance in relevant clinical Gram-positive pathogens.
Similar(12)
The best compound killed multiple S. aureus clinical strains in both planktonic and biofilm forms.
The best compound from these series showed an IC50 value of 1.3 nM.
The best compound in the series showed an IC50 value of 0.4 μM.
The IC50 value for the best compound 3o was 1.5 μM.
The best compound displayed an activity 6-fold higher than chloroquine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com