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On his website, Ross touted 3BP as "currently the best compound to treat tumors".
The best compound killed multiple S. aureus clinical strains in both planktonic and biofilm forms.
The best compound from these series showed an IC50 value of 1.3 nM.
The best compound in the series showed an IC50 value of 0.4 μM.
The IC50 value for the best compound 3o was 1.5 μM.
The best compound displayed an activity 6-fold higher than chloroquine.
These first approach studies help us to choose Ag_Hg3-89.5 Ag_Hg3-89.5s the best compound to perform antimicrobial studies.
The best compound 8 inhibited both enzymes with the IC50 values of 34.8 nM and 26.7 μM.
The best compound showed good in vivo activity when administered intraperitoneally but was not active by oral route.
The best compound of each series, 16 and 31, exhibited EC50s of 39 and 22 nM, respectively.
The best compound from this series had binding affinity (Ki) of 0.4 nM to the human GnRH receptor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com