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The best clinical data demonstrating a long latency for tumorigenesis comes from studying families with familial cancer syndromes.
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Despite the difficulty in categorization of patient groups these data were the best available clinical data.
It is important to know which of these works best on clinical data sets.
The approach used here offers an alternative to aid decision making that takes account of the best available clinical data.
On the other hand, the very best method using clinical data only was very close in performance to the best performing method using combined data.
Therefore, we re-evaluated the EC50 value that best fitted our clinical data.
The review team also further classified the pneumonia episodes according to the probable aetiology, i.e. to bacterial, mixed bacterial-viral and viral infections, by using the best clinical judgement based on clinical data, C-reactive protein concentration, white blood cell count, radiographic appearance and response to treatment with or without antimicrobials.
This estimation gave an optimum EC50 value that would best account for our clinical data of about 28 µmol/l.
Whether OTC (or other data streams yet to be identified) provide the best source of predicting clinical data is still an open question.
Whether OTC (or other data streams yet to be identified) can provide the best source of predicting clinical data is still an open question.
The input for CYP1A2 KI (11.2 μM) was allowed to deviate from the experimental value (2.9 μM) to achieve the best fitting to the clinical data.
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CEO of Professional Science Editing for Scientists @ prosciediting.com