A dietary fibre could be designed that yields the best cholesterol-lowering effect, using experiences in tailoring physicochemical properties and primarily exploiting the biophysical mechanisms of action.
The company is struggling to regain lost sales after its best-selling cholesterol drug, Lipitor, lost patent protection last fall.
Pfizer, which makes the best-selling cholesterol pill Lipitor, said it did not comment on confidential discussions with individual managed care organizations, though it was always receiving proposals.
Price increases for some of the most popular brand-name drugs were much steeper; the sleeping pill Ambien was up 13.3percentt, and the best-selling cholesterol drug, Lipitor, was up 4.7 to 6.5percentt, depending on dosage.
And while everyone knows about Pfizer, and many have seen the television commercials for Lipitor, its best-selling cholesterol pill, the name of Lipitor's generic equivalent, atorvastatin, doesn't exactly roll off the tongue.
A14 SCIENCE/HEALTH Pfizer Wants to Sell Heart Drug in Combination A drug that could be one of the most promising new heart treatments in a decade, called torcetrapib, is generating controversy even before it is approved, because its maker, Pfizer, plans to sell it only to patients also taking the company's best-selling cholesterol treatment, Lipitor.
Reversing a strategy that had drawn criticism from doctors, Pfizer says that it will apply for approval to sell a promising new heart treatment as a standalone pill — rather than only in combination with Lipitor, Pfizer's best-selling cholesterol treatment.
Harry Chip Davisis, another Schering scientist, made another vital realization: that Zetia could be given in combination with one of the best-selling cholesterol drugs called statins.
Pfizer, the world's largest drug company by sales, faces the onslaught of generic competition for its best-selling cholesterol drug Lipitor as early as 2011.
