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As is the case with many insects with recently sequenced genomes [ 4- 8], bees have a much smaller number of known canonical immune response genes relative to Drosophila[ 9], which is one of the best characterized models of insect immunity [ 10].
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SLD is perhaps the best characterized model of dw phenotype.
The mouse retina is one of the best characterized models for in vivo vessel formation as it displays all of the morphological hallmarks of angiogenesis (i.e. sprouting, branching, fusion, remodelling and maturation) after birth (Fruttiger, 2002, 2007).
In vitro differentiation of 3T3-L1 mouse preadipocytes, one of the best characterized models for studying adipogenesis (Green and Kehinde, 1975; Kita et al., 2009), is accompanied by a remarkable increase in the expression of numerous mitochondrial proteins (Newton et al., 2011).
It is also one of the best characterized models for biochemical, molecular and genetics studies among the Lophotrochozoa.
Maybe the best characterized model is the case of ligand dependent transrepression of inflammatory genes.
The best characterized model is the involvement of the RelBE TAS in bacterial stringent response to amino acid starvation.
The Bacillus genus of Firmicutes bacteria is ubiquitous in nature and includes one of the best characterized model organisms, B. subtilis, as well as medically significant human pathogens, the most notorious being B. anthracis and B. cereus.
The genus includes one of the best characterized model organisms, B. subtilis, as well as medically significant human pathogens B. cereus (which causes food poisoning) and B. anthracis (the causative agent of anthrax) [ 13, 29].
The Bacillus genus is ubiquitous in nature and includes one of the best characterized model organisms, B. subtilis, as well as medically significant human pathogens, the most notorious being B. anthracis (the causative agent of anthrax) and B. cereus (which causes food poisoning).
During the analysis of the bank vole heart transcriptome, we used the genomic resources available for the best characterized model mammal - the laboratory mouse.
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