Sentence examples for best characterized function of from inspiring English sources
The provision of metabolic energy by oxidative phosphorylation (OXPHOS) is the best characterized function of mitochondria.
The best characterized function of SMN is its role in the assembly of snRNPs in the cytoplasm, after which a fraction of SMN is thought to be imported into the nucleus, localizing within Cajal bodies and gems [101], [102].
Dismutase activity is the best characterized function of SOD1.
The best characterized function of PCSK9 relates to the binding to LDL-C receptors (LDLR) in hepatocytes.
The best characterized function of TDP-43 is in the regulation of pre-mRNA splicing, including the cystic fibrosis transmembrane conductance regulator (Buratti et al, 2001).
Briefly, the best characterized function of poly(A -tail-bound PA -tail-boundcing trA -tail-boundtiation by interacting with translation initiation factors bound at the 5′-end of the mRNA: this is PABP1sed to stabisizenhancingntranslationinitiationthereby enhancinteractingruitment of ribosomal subunits.
Some of the best characterized functions of PARP-1 and other PARP family members are in DNA repair and the regulation of gene expression, the latter including modulation of chromatin structure, coregulatory functions, and alteration in DNA methylation.
The best characterized functions of RND3 are its inhibitory effect on Rho kinase-mediated biological functions including actin cytoskeleton formation, phosphorylation of myosin light chain phosphatase, and apoptosis 6– 8. Two recent mouse studies revealed an indispensable role of RND3 in mouse neuron development 9, 10.
The inactivation of eNOS through binding to caveolin-1 is the best characterized function for caveolae in endothelial cells [ 37], highlighting their crucial role in vascular homeostasis.
Their best characterized function is catalysis of maturation of spliceosomal and ribosomal RNA by guiding methylation and pseudouridylation of target RNAs in sequence-specific manner [39].
Their best characterized function relates to the signaling pathway of the transmembrane receptor Notch where they mediate the effector nuclear step – activation of Notch-responsive genes.
