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The HSC niche, where MSCs were first identified, is currently the best characterized example of an ASC niche in vivo function of resident MSC in the HSC niche was recently revealed by lineage-tracing using nestin as a marker for MSC.
Perhaps the best characterized example of this is the Muk TE repressor in maize [19].
The best characterized example of this is the response to the binding of ferric citrate by FecA in E. coli.
One of the best characterized example of control of cell behavior by ECM topology has been observed during fibroblast cell migration [15].
Probably the best characterized example of incomplete penetrance in a recessive disorder is provided by the Cys282Tyr (rs1800562) mutation in the haemochromatosis (HFE) gene (Beutler 2003).
Their imposex response remains the best characterized example of endocrine disruption in wildlife, with adverse population-level effects in the low nanogram per liter range for a single chemical, TBT (Matthiessen and Gibbs 1998).
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The best characterized examples of such epigenetic elements are prions, which possess a self-assembling behavior that can drive the heritable manifestation of new phenotypes.
The process of dehiscence in Arabidopsis is among the best characterized examples of endocarp development and lignification.
Kinesin-1 and myosin V are the best characterized examples of motor enzyme molecules that move unidirectionally and continuously along the cytoskeletal filaments (microtubules and F-actin, respectively) that serve as their tracks (1− 3).
The best characterized examples of the family are those found in serine/threonine kinase Akt that are known to bind to PtdIns 3,4 P2 and PtdIns 3,4,5 P3 (PIP2/3) in mediating Phosphoinositide 3-kinase signaling [ 30].
Spiroplasma poulsonii, the best characterized example to date, kills Drosophila melanogaster males only in the presence of all five peptides of the host dosage compensation complex [ 49], and this killing occurs during a narrow developmental period early in embryogenesis [ 50].
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