Sentence examples for best characterised example of from inspiring English sources

miR-210 is the best characterised example of a miRNA that shows substantial induction under hypoxic conditions.

Hypoxically induced miR-210 is the best characterised example of a miRNA that shows substantial induction under hypoxic conditions [ 32, 50] but had no significant influence on the levels of Dicer protein.

We have analysed the extent and prevalence of long-range epigenetic silencing at 2q14.2 (the first and best characterised example of coordinated epigenetic remodelling) and investigated its possible applicability as a non-invasive diagnostic marker of human colorectal cancer using different approaches and biological samples.

One of the best characterised examples of a paralogon includes the genes around the MHC complex on human chromosome 6, with homologues on chromosomes 1, 9, 5, 15 and 19 [ 19, 20] (figure 1).

Classically, cells with high levels of Notch activity suppress the differentiation of their neighbours [ 4], and in some mammalian tissues activation of Notch is associated with tumours, the best characterised example being gain-of-function Notch1 mutations in human T cell acute lymphoblastic leukaemia/lymphoma [ 32].

One well characterised example of plant PCD is the hypersensitive response (HR), a localised cell death induced by pathogen attacks which allows confinement of the infection [2].

The best-characterised case of overlapping tORFs in mammals is that of XL-alpha-s.

A well-characterised example of this is the ribonuclease inhibitor, which binds to ribonucleases in one of the tightest known protein protein interactions.

One of the best characterised transcription factors of the hTERT gene is c- myc (Wang et al, 1998; Greenberg et al, 1999; Kyo et al, 2000; Xu et al, 2001).

Sequence similarity searches were carried out for several of the best characterised members of this functional group with good sequence coverage in our data set.

The best characterised functions of miR-1 are related to the regulation of genes involved in muscle function [29]; in D. melanogaster it is required for post-mitotic growth of larval muscle [30], targeting mRNAs that impair muscle development [28].