Sentence examples for best binding and from inspiring English sources
Disaccharides 4 and 9, having a modified carbamoyl group at the C-2 and C-3 positions of the d-mannose and d-altrose subunits, respectively, exhibited the best binding and uptake profiles in all four cancer cell lines studied.
The best binding energy values and their corresponding rank and run numbers were depicted in Table 4.
The alleles with high frequency within human population and with significant binding data were selected and the best binding peptides for each allele were identified and highlighted on the cartoon structure of Bm-iPGM and these were mainly located in the α-helix region of the structure.
Here, all IgG varants bound weaker than their scFv-Fc analog with HT186-D11 showing the best binding to T47D cells, and huHMFG1 (only analysed as IgG) showing the lowest binding to MUC1.
The results conclude that out of 55, 19 molecules possessed best binding energy (< −3.333 kcal/mol) and these molecules had more selective and safer COX-2 inhibitor profile compared to the standard celecoxib.
Also, 3i and 3s have shown similar binding to that of the co-crystallized ligand inside the active site of M. tuberculosis enoyl reductase InhA and the best binding score in this series.
In the service selection problem the objective is to look for the best binding to operate between abstract and concrete operations in order to optimize the quality of the service composition.
The 20 best binding poses for each fluoroquinolone and dione were obtained by first docking with the 2XKK topoisomerase IV crystal structure of cleaved complexes formed with moxifloxacin.
Brigati et al. proposed a method based on landscape pIII phage-display libraries (that contain thousands of copies of peptides best binding to a specific antigen) and phages expressing a specific peptide used as a probe that specifically binds to B. anthracis spores [ 81].
Among those synthesized compounds, the compounds 1 24 and 1 26 showed the best binding affinities to the 5-HT7 receptor with Ki values of 43.0 and 46.0 nM, respectively.
Out of the aforementioned docked molecules, B15 and B16 showed the best binding energies of − 11.15 kcal mol− 1, − 10.70 kcal mol− 1 and − 10.49 kcal mol− 1, − 10.12 kcal mol− 1 against EGFR and HER2 protein receptors, respectively.
