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Exact(3)
Sensitivity of Bowtie2 was set for the best alignment of each read (−−b2-very-sensitive).
To calculate these thresholds, we consider all alignments of each read as opposed to just the best alignment of each read since misassembly errors frequently occur within repetitive regions where the reads will align to multiple locations.
Only the best alignment of each query sequence was chosen, and alignments were clipped from both ends to the start of the first match and the end of the last match positions.
Similar(57)
When the longest alignment is more than twice of the second one in length, we consider it as the best alignment of this scaffold and link the wild goat's scaffold with the aligned loci in the domestic goat's chromosome.
The best alignment of fibrils was observed at intermediate shear rates of 20 and 80 s−1.
The DTW search looks for the best alignment of the query and a partition of the normalized cost matrix corresponding to a speech segment.
The LB pharmacophores included exclusion volume spheres that were automatically generated around the best alignment of the ligands used for the creation of the pharmacophore.
The best alignment of a query in an utterance is defined as the one that minimizes the average distance in a warping path of the normalized cost matrix.
With this new block, the task is to search for a best alignment of the input sequences allowing the use of gaps, matches, mismatches and differences.
As this conforms to both the 196aa and 28aa charge periodicity (98aa = 7×14aa), this staggering should provide the best alignment of charges.
Since the control samples are actually samples from the trial, the parameter settings resulting in the best alignment of this representative control sample set will then also result in the best alignment of the entire sample set.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com