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The resulting data revealed that besides the expression of nestin (69.39%±12.25), subpopulations of the cells already express β-III-tubulin (21.8%±3.3), GFAP (9.33%±3.72), and α-SMA (29.72%±8.26) before the initiation of the differentiation.
Thus, it appears that besides the expression of multiple Nlrp1b splice variants, CAST/EiJ mice have many more unique characteristics.
Here, besides the expression of CXCR4 in feline mammary tumours, we also investigated the functional role of this receptor in mediating proliferative signals.
Significant increase in the activity of P5CS (Fig. 5a), besides the expression of its gene (Fig. 3, 4), also indicated possible accumulation of proline in the plant in addition to glycinebetaine upon salt treatment.
The cocultivation of rBM-MSCs with islets and STZ-damaged islets showed the expression of IL6 and transforming growth factor- β1 in the culture medium, besides the expression of the antiapoptotic genes (Mapkapk2, Tnip1 and Bcl3), implying the cytoprotective, anti-inflammatory and antiapoptotic effects of rBM-SCs through paracrine actions.
Besides, the expression of PK at the mRNA level was also induced by the HRW treatment.
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At the acute stage of infection, besides IFN-γ, the expression of IL-4 and IL-10 in the Vac-Cha group increased significantly at week 6 post-challenge.
Furthermore, besides noticing that the expression of both these transcription factors was mutually exclusive in some cells, many others were clearly Sox2+/Olig2+.
These compounds inhibit hypoxia-induced HIF-1 activation; besides, they may affect the expression of HIF-1 and HIF-1 target genes including GLUT1.
Interestingly, besides V-ATPases, mTORC1 regulated the expression of multiple lysosomal genes.
Recent studies have shown that besides causing a potent stimulation of the expression of numerous genes participating in the fibrotic process, TGF-β is involved in the generation of myofibroblasts through EndoMT [ 21, 22, 38- 42].
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