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Besides the difficulties of asynchrony, clock skews, and network delays, an additional source of complexity comes from the multirate nature of many such systems, which must implement several levels of hierarchical control at different rates.
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Neither had Himalayan experience, and they were faced with the problem of acclimatization besides the difficulty of the terrain.
An adaptation of Watchmen, the classic graphic novel that finally made it to the screen this year directed by Zack Snyder, passed across his desk twice; besides the difficulty of raising funds for such an ambitious film, Gilliam decided the original material would be better served by a mini-series.
The security of the enterprise system emerges as a growing problem besides the difficulty of the creation of complex systems.
Hence, besides the difficulty of deciding between bias due to cDNA libraries enriched in 3'-end-transcripts, and the presence of transcripts of pseudogenes in the transcriptome, we hypothesize that the distinct stability and translational rates of the messengers might also contribute to the observed differences between transcriptome and proteome.
He described the difficulties of competitive skating.
"I know the difficulties of people.
The difficulties of life support are considerable.
The difficulties of self-control.
Strive, despite the difficulties of existence.
"Women in Turkey live with the difficulties of secularism not the difficulty of Islamists," she says.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com