Sentence examples for besides the activation of from inspiring English sources

These data point to an additional GPR55-independent effect of LPI besides the activation of a non-selective cation channel.

A number of mechanisms may underlie the ability of nanoparticles to cause genotoxicity, besides the activation of ROS scavenging mechanisms.

Moreover, Bid-mediated activation of the intrinsic mitochondrial apoptotic cascade had only a mild effect on the sensitization observed upon uPA depletion, suggesting that other molecular mechanisms besides the activation of the intrinsic mitochondrial cascade underlie the sensitization to TRAIL in uPA-depleted cells.

Besides the activation of KATP channels, GLP-1 is also involved in modulating the activity of the voltage-gated potassium channels (Kv) [ 3, 8, 9].

Besides, the activation of microglia was considered as the major mechanism to assist plaque clearance in the studies of Leinenga et al. and Jordao et al.7,8 These reports post strong implication that the proposed mechanism (microglia activation) is convincing and should be independent to the animal model.

Besides the activation of HSCs, chronic hepatocyte injury is another key step for hepatic fibrogenesis.

In our system, besides its effect on the activation of AKT, LY294002 caused a decrease in ERK activity (Figure 2), suggesting a functional relationship between the two kinases.

In particular, we find evidence that the activation of intragenic enhancers, besides affecting the activity of internal TSSs, can also potentially influence the inclusion of nearby exons.

The activation of both regions activates the metaphorical link.

Indeed, besides inhibiting Akt activation, the combination treatment also repressed the activation of certain MAP kinases, including ERK and p38 (data not shown).

The results from this study indicate that besides the mechanisms directly driving cell death in the brain during BM, such as the activation of pro-apoptotic genes, brain injury is further modulated by mechanisms controlling cell growth and neuroplasticity.