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Clear upregulation of IFN-inducible genes (ISGF3G, IFIT3, G1P2 and IRF1) was identified, besides increased expression of genes related to lymphocyte development and activation, and antigen processing and signal transduction.
Besides, increased expression of hepatic PKR transcripts confirmed that each enrolled mouse was properly challenged by the poly I C (Supplementary Fig S3D).
Besides, increased expression of M-CSF (P = 0.034), Ki67 (P < 0.001) and TGF-beta (p = 0.003) in tumor correlated significantly with a shorter DSS, (Table 2 and Figure 2).
Besides, increased expression of one or more of the three NOS isoforms has been shown in the spinal cord of rodents after carrageenan injection into a hindpaw [ 13], intraplantar injection of CFA [ 12] and formalin [ 14], and intradermal injection of capsaicin [ 15].
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Increased expression of miR-200c-3p miR-200c-3p miR-200c-3protein expression.
These events may facilitate increased expression of these genes.
Patients with del 5q) MDS have decreased expression of miR-145 and increased expression of Fli-1.
Increased expression of adiponectin was also detected.
Differentiation increased expression of EPHB2 and EPHB3.
Paradoxically, there was increased expression of DNAJC3.
More interestingly, we observed that the increased expression levels of FXYD6 were positively correlated with the enhanced protein levels of Na+/K+-ATPase α1 (Fig. 3C and 3D), indicating that FXYD6 exerts its regulatory effect on the holo-enzymatic activity of Na+/K+-ATPase through up-regulating the protein levels of Na+/K+-ATPase α1 besides the direct interaction with this enzyme.
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