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The conformational dynamics of all the complexes can be described in terms of three classes of DNA conformations: slightly bent/unbent (U), intermediately bent (I), and strongly bent (B); however, the relative stabilities of these states and their rates of interconversion vary dramatically for the different complexes.
In fact, the conformational properties of both wild-type and mutant (see below) MutS bound to all of the mismatches studied can be effectively compared using these three dominant classes of DNA conformations: unbent/slightly bent (U; FRET values of 0.30 0.40), intermediately bent (I; FRET values of 0.4 0.55), and significantly bent (B; FRET values of >0.55).
"Whether that means that any of them are in anyway bent I would dispute.
As I lay down, I had to keep my knees bent; I would evidently endure eternity in modest discomfort.
When I ate a few nights later at Taboon, restaurant in Midtown with an Israeli chef and a Middle Eastern bent, I had grilled foie gras, skirted with a green tomato marmalade.
To the nobodies, forgotten, heartbroken, and bent, I feel your pain.
Similar(53)
In poplar, PtaZFP2 mRNAs accumulated strongly and rapidly after stem bending, i.e. mechanical loading.
"But what can I do; I can break but not bend; I never could".
"I couldn't bend; I still can't," said Ms. Maynard, who walks with a cane.
An example of a statement is: "Due to long and frequent lifting and bending, I have an increased risk of low back pain.
(032, line 293) If I bend, I know I will irritate my back…if it is going to irritate me for half an hour when I could achieve half an hour painfree, why would I do that?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com