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Our analysis demonstrated a high incidence of benign and malignant abnormalities in the mammary glands in the parental "control" FVB mice (see above).
In addition, our analysis demonstrated a high incidence of benign and malignant abnormalities in the mammary glands in the parental "control" FVB mice, which have important consequences for the interpretation of new phenotypes in transgenic mice in a FVB-background.
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For example, a blood-based gene-expression test could assist mammography in discriminating between benign and malignant breast abnormalities.
Table 6 reports the diagnostic performance of mammography, US, mammography/US, and DeHCA score in the detection of breast abnormalities, including benign and malignant cases versus negative cases (no abnormalities).
This article is the first to describe the induction of numerous abnormalities, including both benign and malignant lesions, in reproductive tissues of aged female mice exposed prenatally to a broad range of BPA doses (0.1 1,000 μg/kg maternal body weight).
These abnormalities included goiter, thyroiditis, benign and malignant primary neoplasm.
VA can be used to detect various breast abnormalities, including calcifications and benign and malignant masses, with relatively high specificity.
We divided the findings into two clinically relevant categories: neoplastic (benign and malignant tumours) and non-neoplastic (cysts, structural vascular abnormalities, inflammatory lesions, and "other" such as hydrocephalus, Arnold-Chiari malformations, and extra-axial collections).
In this study, we collected and compared benign and malignant breast stem/progenitor cells to determine whether specific genetic abnormalities occur in breast cancer stem/progenitor cells within the human body.
The data accumulated to date implicate abnormalities in the VEGF pathway as a common event across the spectrum of benign and malignant vascular neoplasias (Fig. 1).
Evaluation of brachial plexus abnormalities represents a diagnostic challenge due to anatomical complexity and to overlapping presentation of both benign and malignant conditions.
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