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In such settings, benefits of continuation of TMP-SMX may still outweigh the risks associated with earlier discontinuation of TMP-SMX after programs of antiretroviral therapy is increasingly implemented in these regions.
Even though the present study design did not expressly provide for any follow-up and no data are therefore available to substantiate the authors' claim, they do have good reasons to believe that with regard to a number of former study subjects the obvious benefits of continuation proved a persuasive enough argument.
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We assessed the efficacy of continuation treatment with antidepressants in a meta-analysis of relapse prevention studies in the five principal anxiety disorders, to explore the benefit of continuation treatment in each disorder, and their relative efficacy across these disorders.
A survival benefit of continuation of beta-blocker therapy in patients with ADHF was demonstrated by Butler et al. [ 20] and recently confirmed by Fonarow et al. [ 21], Jondeau et al. [ 22] and Orso et al. [ 23].
In high-risk patients (those with femoral neck T-scores 2.5 T-scores 2.5 bisphorphonates for 3–5 years, the benefit of continuation from the aloweronate 'Fosamax Long-Term Extension' trial seems to far outweigh the risks.
The benefits of using continuation are clearly demonstrated for both codes for a large class of problems.
Yet, despite these limitations, the overall results provide further evidence to support the benefits of donepezil continuation, and of memantine treatment despite discontinuation of donepezil.
Also it will be assessed what impacts can be expected (the real difference for the beneficiaries for each of the results areas, plus unintended positive or negative results if any) and sustainability (long-term benefits, continuation of generation of benefits after completion of the programmes).
While, granted, it stings to lose out on more potential revenue, what Obama did secure was an extension of unemployment insurance benefits, a continuation of tax provisions like the Earned Income Tax Credit (EITC), the childcare tax credit and college tuition tax breaks – all of which disproportionately affect the poor and the middle class.
The enhanced benefits include continuation of an employee's base salary, as well as dental and health benefits, for 4 to 24 months, depending on an employee's job level, the company said in its filing.
Although it is not clear why patients would continue to benefit from continuation of trastuzumab in the setting of disease progression, it is possible that HER2 inhibition may continue to provide synergy with different chemotherapeutic agents administered sequentially.
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