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Location of SLiMs in intrinsically disordered regions provides several important functional benefits for interactions with domains.
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For similar dyad members, there was no relative benefit for interaction over the MCS algorithm (Semp /SMCS ≈ 1 when Smin /Smax > 0.8).
However, for dissimilar dyad members, there was a relative benefit for interaction over the MCS algorithm (Semp /SMCS > 1 when Smin /Smax < 0.8).
Similarly, differences were more pronounced in meta-analyses with large estimated treatment benefits in the overall meta-analysis compared with meta-analyses with small estimated benefits (P for interaction <0.001) and in meta-analyses of complementary interventions compared with conventional medicine (P for interaction <0.001).
A combination score of positive pathway markers including p-Akt, p-mTOR, and p-ER showed significant association with tamoxifen benefit (test for interaction; P = 0.029).
Furthermore, also providing benefit for subsequent interactions, optimization algorithms must be applied.
As Torgerson and Sibbald state, patient preference trials are not meant to replace randomised trials, but to complement them, although measuring a patient's preference maintains all the advantage of a RCT, but has the benefit of allowing for interactions between preference and outcome to be assessed [ 20].
Furthermore, we developed a simple model to show that, rather than requiring prohibitively strong selection to effect a change in binding preference, it is reasonable in many cases to expect that such a change can occur with only small selective benefits for the modified interactions.
The enhanced electric field is located in the center area of nanochannels, which can be further benefit for analytes interaction experiments.
For VANA, this organic process benefited from interactions between the partnerships and also from the involvement of VA Headquarters personnel.
Young age and low malignancy grade were associated with a relative benefit for HD (tests for interactions: P = 0.04 and P = 0.0057, respectively).
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