Her2 overexpression is associated with a diminished prognosis (e.g., higher risk of recurrence); however, it also predicts that a patient will more likely benefit from directed therapies that target Her2 (Trastuzumab, [ 17]).
In principle, this ought to reflect all the anticipated costs and benefits, direct and indirect, that impinge on company values.
This is not the vision of some "EU Superstate" that the 'out' campaigns desperately try to paint, but a union of economic co-operation that brings benefits direct to the back pockets of British families.
To take just one example of these direct benefits, that of potentially increased access to physical exercise, this study has identified some possible mechanisms for the recently reported finding (Webb, Netuveli and Millett 2012) that access to free bus passes for older citizens leads to reductions in obesity.
This development had two direct benefits that would facilitate the process of liberalization.
Women were disproportionately denied the direct benefits that might come from study participation.
One particular direct benefit that has attracted significant attention is that of fertility assurance, as females often need to mate multiply to achieve high fertility.
It is our view that, on occasion, it is acceptable for children to make their own decision about whether to consent to participate in research with a prospect of direct benefit that has been approved by relevant ethics committees.
Corporate social responsibility (CSR) practices that benefit direct and indirect stakeholders such as customers, employees, society, and the environment are a key pillar in this trend toward cooperative value creation.
Banks "need to be willing, like the regulator, to recognize that there are some profitable activities so unlikely to have a social benefit, direct or indirect, that they should voluntarily walk away from them," Mr. Turner told the group.
