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Besides the objective HA benefit with regard to speech understanding in quiet and noisy conditions, the subjective benefit was assessed using the IOI-HA inventory.
The predictive value of each marker and molecular subtype for the docetaxel benefit was assessed using a Cox regression model with terms for treatment by marker interaction, with and without adjustment with the variables quoted above.
Hearing aid benefit was assessed using objective measures regarding speech recognition in quiet and noisy environments as well as a subjective measure reflecting everyday situations captured using a standardized questionnaire.
The predictive performance for tamoxifen benefit was assessed using two ER+ BC populations treated either with adjuvant tamoxifen only (n = 77+139) or first-line tamoxifen for advanced disease (n = 270).
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The dosimetric benefit is assessed using a comparative dose-volume histogram that shows the volume of bladder irradiated when the patient is treated with conventional, conformal and IMRT plans (Fig. 6).
Sun protection behavior benefits were assessed using a measure developed by Glanz and colleagues [ 28].
Benefits were assessed using diclofenac 150 mg/day, naproxen 1,000 mg/day, ibuprofen 2,400 mg/day, celecoxib 200 mg/day, and etoricoxib 60 mg/day.
The subjective benefit experienced in everyday life was assessed using the widely used IOI-HA.
Minimally desired benefit from PRT (local control) was assessed using the Treatment Tradeoff Method.
Minimally desired absolute benefit (local control) from PRT was assessed using the Treatment Tradeoff Method (TTM) (Llewellyn-Thomas, 1997).
Cost-effectiveness was assessed using the net-benefit approach and cost-effectiveness acceptability curves.
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