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The conditions for acceptance of evidence for clinical benefit vary among national HTA agencies since the structure of the health care systems differs greatly from country to country.
Here, I present results from an agent-based model designed to answer two qualitative questions: are clustered nests more or less successful than dispersed nests, and how does that relative benefit vary depending on predator behavior?
As the magnitudes of OS benefit vary depending on IL8 genotypes, alternative sequencing or combination treatment strategies that are based on genotyping could be explored in the future as new therapies become available.
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Among those who responded to ketamine, the duration of benefit varied widely, from 25 days to eight months, with the median 2.3 months.
In this population, the tamoxifen benefit varied by Recurrence Score and was greatest for those with low Recurrence Score values.
The probability of an isolation benefit varied widely across the units, e.g. 27-82% under the full model.
Estimates of the effectiveness of barrier precautions showed an overall benefit of 25%, but this benefit varied widely across different types of ICUs.
Although there was consistency in informing patients that a cure was not being sought, the amount of information given about survival benefit varied considerably (table 3).
Efient® (prasugrel), Inovelon® (rufinamide), Gylenya® (fingolimod), Levact® (bendamustine) and Ellaone® (ulipristal), for which the improvement in actual benefit varied from "no improvement" to "modest improvement".
But benefits vary widely from plan to plan.
Benefits vary from one legal jurisdiction to another.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com