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These differences in clinical benefit remained significant after adjusting for other clinical variables, including grade and tumour size.
It would be interesting to know whether this mortality benefit remained significant if the randomization had been to nonintermittent positive pressure ventilation versus invasive ventilation.
In the present series, the prognostic value of Ki67 and its value predictive for docetaxel benefit remained significant in multivariate analysis when we applied a 15% cut-off (data not shown), regardless of the cut-off for ER and PR: 1% (P = 0.028 and P for interaction = 0.033 respectively) or 10% (P = 0.022 and P for interaction = 0.031 respectively).
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We then set up a mother-removal experiment using 40 clutches to test whether (4) low maternal expenditure on egg care can be beneficial to the female, e.g. in terms of 2nd clutch production, and whether (5) these benefits remain significant after females interact with their hatched nymphs [ 18, 19, 22, 25].
The estimates for the benefits variables remained significant after inclusion of the Townsend score in the respective models, with the exception of income-based job seekers allowance in which both variables were significant.
The benefit of acupuncture remained significant when the analysis was limited to two studies with a low risk of bias.
However, when we limited our main analysis to those studies rated as having a low risk of bias for randomization/allocation concealment, the benefit of acupuncture remained significant.
Among individuals meeting the original criteria for insulin autoantibodies (IAAs) (≥80 nU/mL), the overall benefit of oral insulin remained significant (P = 0.05).
In a logistic regression model, the odds ratio for the harm of blood group A or AB or the benefit of group O remained significant even after controlling for numerous clinical factors including HbS (Fig 3).
The association between HD-CTC benefit and the BRCA-likeCGH status remained significant with relatively few patients switching classes.
In the fully adjusted model, only uncertain and negative RTW-expectations remained significant predictors of benefit recipiency (table 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com