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However, this potential benefit must be critically examined in a large RCT.
When prescribing statins, any drug risk and benefit must be taken into account.
Any private entity that might benefit must be clearly reported.
Second, positioning on a particular benefit must be profitable.
That mutual benefit must be something worth pursuing.
Public benefit must be legally construed in the light of modern economic and social circumstances.
Some balance of cost and benefit must be assessed other than by those with a commercial or political interest.
Benefit must therefore significantly outweigh the risk of carrying out treatment in such patients (Figs. 7 and 8).
Finally, the implications for the patient and clinician, and issues of fair access and benefit, must be fully addressed.
For a car shopper to buy a diesel model, he said, the perceived benefit must always equal or exceed the cost.
But that benefit must be weighed "against the increased toxicity, including deaths" associated with use of the drug, the F.D.A. staff said.
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