Sentence examples for benefit mice from inspiring English sources
Consistent with cathepsin cleaving wild-type APP more efficiently than mutant APP, cathepsin B inhibitors did not benefit mice expressing mutant APP [ 43].
Many pathogens hitch a ride in the saliva, and they, too, seem to benefit: Mice develop more severe infections when a virus is injected by a mosquito than by a researcher using a needle.
There is also evidence that increased pAMPK benefits mouse models of DCM [ 23].
Importantly, the co-transfer of a population of co-purified/co-expanded Teffs did not negate this therapeutic benefit in mice.
This vaccination approach provided long-term survival benefit for mice challenged with neu-expressing tumor following as little as 2.7 μg of HER2 protein incorporated in the vaccine.
Furthermore, administration of blocking monoclonal antibodies to RAGE, even when delayed by 24 hours, afforded survival benefit in mice subjected to this procedure.
There was a significant survival benefit in mice infected with live E. coli (100% vs. 20%, p = 0.013) or S. aureus (60% vs. 20%, p = 0.02) when treated with ATL313 in conjunction with an antibiotic versus antibiotic alone.
Log-rank (Mantel Cox) tests of the plots revealed a significant survival benefit in mice expressing wtBRG1 (groups 2 and 5; mean ± SD survival time of 125.8 ± 15.8 days) compared with groups 1 and 4 (70 ± 5.2 days; p = 0.003) and groups 3 and 6 (87 ± 6.5 days; p = 0.026; Fig 6B).
The second study asked whether inhibition of the miR-34 family (miR-34a, -34b and -34c) by a subcutaneously delivered 8-mer LNA could provide a therapeutic benefit in mice with preexisting pathological cardiac remodeling and dysfunction due to MI (Bernardo et al, 2012).
FGFR3 injections benefitted the mice in another way, cutting their mortality rates by more than two-thirds.
Endothelin antagonists recently shown to be of benefit in mouse models of sickle disease [13] likely exert their effect through KCa3.1 inhibition and consequent reduction of erythrocyte dehydration[14].
