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In conclusion, this updated analysis of NEAT and BR9601 trials at 7.4 years median follow-up adds to the EBCTCG data in respect of the advantage of anthracyclines and confirms E-CMF as a highly effective standard adjuvant therapy for early breast cancer, with a benefit maintained through time in longer follow-up.
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Clinical benefit was maintained through Week 56 in all effectiveness parameters.
Importantly, the favourable effect of ivabradine on HF events became apparent within 3 months of initiation of treatment, and the benefits were maintained through the course of the trial.
Resistance developed in fewer than 1% of subjects who were switched to rilpivirine-emtricitabine-tenofovir, and this switch also resulted in improvements in fasting lipids and adverse events; the latter benefits were maintained through the 48-week period of the study.
The fully human anti-tumor necrosis factor (anti-TNF) antibody adalimumab reduces the signs and symptoms and improves overall quality of life in patients with active AS; these benefits have been maintained through 2 years of treatment.
One provides evidence that the benefits of adding aprepitant are maintained through multiple cycles of chemotherapy (de Wit et al. 2004), with complete response in the sixth cycle in 59% of the aprepitant group, compared with 40% for standard therapy (Table 4).
Their governments benefited from sectarian unity, which they maintained through bullying and haggling.
This benefit in VA in ranibizumab-treated patients was maintained through 24 months (Rosenfeld et al. 2006a).
Evidence suggests cooperation will be maintained through indirect and direct fitness benefits (Griffin and West 2002).
Private companies benefit by using specialists who are trained and have their professional standards maintained through another body – the NHS.
These benefits were achieved as early as week 10 and were generally maintained through week 54.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com