Exact(8)
Poor compliance or lack of perceived benefit led to discontinuation in 3 additional subjects after V2 (2 siblings with type II, a 5 year old girl and 7 year old boy, and a poorly compliant 3 year old boy with type II who repeatedly refused oral dosing).
Increasing the assumed length of treatment benefit led to reduced ICERs in all scenarios.
This drug's vast therapeutic benefit led to it being featured on the cover of Time magazine and coined as the "magic bullet" to cure cancer [13].
This small benefit led to frequent use of this treatment as a standard option in the US, even though two-year survival remained negligible.
Prospectively identifying sensitive or excluding resistant patient populations to achieve definitive clinical benefit led to successful development of several targeted therapies.
In agreement with the independent review committee of the study, these serious adverse events and apparent lack of therapeutic benefit led to the early termination of ISRCTN445828668.
Similar(52)
These benefits led to enhanced cytocompatibility for both cell adhesion and encapsulation; furthermore, the increased physical strength provided for the generation of a micro-engineered tissue scaffold.
It is noticeable that post-2008, and continuing under the Coalition government, the tightening of conditionality requirements for working-age people in receipt of disability benefits led to declines in the inflows and stocks of people on such benefits.
These benefits led to higher yields of yacon tuberous roots, most notably the double-sided plastic film cover (31.71 Mg ha−1) and coffee husk at level 2 (28.35 Mg ha−1).
Although people who leave TANF usually remain eligible for Medicaid, confusion regarding eligibility and time limits for cash benefits led to a high proportion of uninsurance [20].
Their benefits led to an increasing amount of applications in many sectors including electronics, clothing, medicine, cosmetics and food [ 1].
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