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"Plenty of things in medicine cost a lot and the benefit is questionable.
Survival benefit is questionable and modest at best, and there are significant concerns for harm such as decline in functional status, high treatment and symptom burden, poor QoL, aggressive end-of-life care, and institutionalized death.
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However the findings from one of the four studies showing a significant benefit are questionable because of failure to control for diabetes medications and poor adherence to the prescribed diets.
The metformin concentration utilized in the diet is approximately 10 times that of the highest dose used in human treatments, implying that any increase necessary to observe life span benefits is questionable for a human application [ 75].
F.D.A. approval of new drugs commonly opens the floodgates to widespread use, often by many patients for whom the benefits are questionable.
This survey puts the initiative in a negative light, as its foundations are shaky, its benefits are questionable, and its drawbacks can be serious.
Although the program was not all that popular with the American public and its benefits were questionable, its lightning fast impact impressed the hyperactive news media.
Privacy advocates argue that the benefit to security is questionable and the intrusiveness is high.
However, the decrease in humidity and temperature may be slow and the benefit on nebulization is questionable [23].
23 Although PSA testing is useful for early diagnosis, its value as a screening tool has been under scrutiny because the theoretical benefit on mortality is questionable.
The predictive value of MP regarding the benefit of CHT is questionable and this was the main reason for not adding cytotoxic treatment in these patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com