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While the relationship between CD16A polymorphism and benefit is controversial for cetuximab [ 12- 15], CD16-158V and CD32A-131H homozygosity appear to be associated with beneficial responses for rituximab and infliximab [ 16- 18].
Previous studies have shown a reduced incidence of VAP with the use of inhibitors of biofilm formation, such as silver coating of the ETT, although mortality benefit is controversial [ 1].
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The prescription drug benefit was controversial when it first passed in 2003.
While extending the benefits is controversial among Republicans, it is more popular right now than the extension of the payroll tax cut.
The discounting of future health benefits is controversial [26] [28].
However, sexual selection based on genetic benefits is controversial, and there is limited unambiguous support for the notion that choosy or polyandrous females can increase the chances of producing offspring with high viability.
Methods for valuing such benefits are controversial.
Long term benefits are controversial and in paediatric cases, raise concern about risks of epiphyseal growth plate damage and post radiation sarcoma [ 4, 5].
Cost-benefit analysis is controversial in an age of skepticism over further market acceleration: "T+2 is probably one step the industry could find a way to cope with.
Moreover, the benefit of steroids is controversial in immunocompromised patients and in patients with severely altered mental status at hospital presentation.
Radical resection without rupture is the standard therapy and the most important prognostic tool [46], but whether lymphadenectomy or adjuvant chemotherapy provide benefit is still controversial [11, 12, 19, 21, 27, 29, 31, 36].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com