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Risk and benefit in specific research contexts, including (a) approaches to risk assessment and risk reduction, (b) understanding and maximizing benefit, (c) risk/benefit assessment to justify a given research procedure.
Despite their traditional use as lipid-lowering agents, hypothesis-generating works have suggested that statins may show benefit in specific enriched HF subgroups.
While no mortality difference was detected between groups in the main analysis, several subsequent analyses have suggested benefit in specific subgroups of patients.
Gene gain, via acquisition of genomic islands, likely confers a fitness benefit in specific habitats.
The use of natural alkaline compounds against cancer is relatively non-toxic and may provide benefit in specific cases.
Acquisition of foreign genomic islands likely confers a fitness benefit in specific habitats, notably plant-associated niches.
Similar(51)
Often when studies do not meet the primary endpoint, it is common to explore possible benefits in specific subgroups of patients.
It was found that even though there are no environmental benefits in specific environmental impact categories for certain biomass systems (Fig. 2), each aggregated biomass system performance results in benefits compared to its reference system.
This is an example of regulators responding to a public health need and being willing to adopt a different view of the risk-benefit in specific circumstances.
However, risks may outweigh benefits in specific age groups [ 39] and different subsets.
Careful dissection of melanoma into more homogeneous subgroups may be essential for identification of treatment benefits in specific subcategories of patient.
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