Exact(1)
However, the absence of statistical testing and the reliance on mere descriptions of the alleged benefit in majority of the pharmaceutical industry initiated post-authorization NI trials bring us back to the evidence-problem we discussed earlier.
Similar(59)
Over 60 patients affected by SCID due to IL2RG deficiency (SCID-X1) or adenosine deaminase (ADA -SCID hADA -SCIDved havetopoietic stem cell gene thereceivedthematopoieticarsteming gammaretroviral vecells, resultingene immune reconstherapyn and clinical benefithen the majority of them.
However, our model predicts no therapeutic benefit in the majority of cases (Supplementary Figure 6 and 7).
Treatment with vitespen did not result in a discernable benefit in the majority of patients with metastatic RCC treated in this study.
In a phase 2, non-randomized trial in subjects with metastatic renal cell carcinoma (mRCC), vitespen failed to provide a clinical benefit in the majority of subjects.
This study indicates that rituximab, given as post-remissional therapy in older CLL patients treated with chlorambucil and prednisone produced a clinical benefit in the majority of cases.
In summary, short-term treatment with adalimumab for 12 weeks in patients with inflammatory OA of the knee refractory to conventional treatment resulted in clinical benefit in the majority of patients using the OARS I/OMERACTresponder index.
Although no randomised, placebo-controlled trials using PRRT exist, PPRT with Yttrium-labelled SSAs has been shown to cause tumour regression and symptomatic benefit in the vast majority of patients (Waldherr et al, 2001, 2002; Kwekkeboom et al, 2005b; Imhof et al, 2011).
Finally, while children and their families benefit in the studies, the majority of benefits accrue to the rest of society.
This is not the America of investing tax revenue in programs to benefit the majority, like the U.S. interstate highway system, and in regulation to benefit the majority, like the U.S. Consumer Product Safety Commission (a chicken coop now being "guarded" by a fox formerly employed by the corporate-dominated U.S. Chamber of Commerce).
The topic has been the focus of much debate on the grounds that the proportion of individuals with elevated cholesterol values is high in most Western populations, and that the costs for treating all these people with drugs life-long would be enormous, with a marginal benefit in risk reduction for the majority of them [ 1- 3].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com