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Finally, two small open label trials of VPA in human subjects have reported modest strength or functional benefit in a subset of those patients [30], [31].
Enzyme replacement therapy (ERT) with alglucosidase alfa has resulted in a clinical benefit in a subset of patients.
Antitumor activity was observed in 5/40 (12.5%) of evaluable patients, suggesting the possibility of clinical benefit in a subset of melanoma patients.
Along with others, we have shown that combination therapy with ATRA and VPA is of clinical benefit in a subset of AML patients.
However, prospective randomised clinical trials are needed to demonstrate whether the patient selection itself or its combination with high-dose IL-2 leads to the observed significant clinical benefit in a subset of patients.
It must be noted however that STn expression was not evaluated as a prerequisite for study entry and therefore the possibility of a benefit in a subset of patients whose tumours expressed STn could not be excluded.
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It may be that the adverse relationship between vasoactive agents and survival actually comprises a combination of incremental benefits in a subset of patients that are outweighed by incremental harms in another subset.
The mechanisms which explain the survival benefit seen in a subset of patients treated with lung dose reduced, twice daily TBI remain unknown[ 19].
R0 resection is associated with dramatic survival benefit over R1 resection in a subset of patients with tumor size ≤25 mm and ≤1 involved LN.
53 Although, in the study by Hodi et al, 50 the difference in the median overall survival in the two groups receiving anti-CTLA-4 versus the gp100 alone group was only 4 months, the true impact of the anti-CTLA treatment was in the long-term benefit which was observed in a subset of patients.
Longer and longer parental leave perks benefit only a subset of workers: Those who've just welcomed a crying, all-consuming newborn into their lives, or in some cases, adopted a child of their own.
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gain in a subset
benefit in a fraction
benefit in a phase
benefit in a series
benefit in a screening
benefit in a turnaround
benefit in a variety
benefit in a user
benefit in a downturn
benefit in a profusion
benefit in a lump
benefit in a process
benefit in a combination
benefit in a subpopulation
benefit in a room
benefit in a number
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