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For patients with FLT3-ITD mutations, the addition of the FLT3 inhibitor CEP-701 to chemotherapy at relapse did not result in any survival benefit in a recent randomized study.
Nevertheless, display of preoperative tractography without correction for brain shift was of benefit in a recent series of patients undergoing extratemporal lobe resection for epilepsy (Sommer et al., 2013), although in only a minority was the optic radiation the tract of interest.
The tyrosin kinase inhibitor gefitinib, directed against the tyrosin kinase domain of the EGFR, showed single-agent activity against SCLC cells (Tanno et al, 2004), and reverted resistance to the chemotherapeutic topotecan in vitro (Nakamura et al, 2005), but failed to show clinical benefit in a recent phase II clinical trial in patients with SCLC (Moore et al, 2006).
The small number of controlled studies that were performed failed to demonstrate a significant benefit – with the exception of cyclophosphamide, which showed a modest, statistically significant benefit in a recent randomized controlled trial [ 5], and to a limited extent methotrexate for early active disease [ 6].
This improvement in cardiac function has been shown to translate to a symptomatic benefit in a recent trial by Davies et al. (2013), which assessed seven patients with chronic heart failure with reduced LVEF receiving renal artery denervation therapy over a six-month period.
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When asked whether health care reform should be funded by taxing health care benefits in a recent poll, only 19% favored the idea, while 77% opposed.
Jim Gattis, a member of the hospital's board of directors, has defended Downing's benefits, arguing in a recent editorial that the public hospital had to offer compensation on par with private hospitals in order to hold onto the best talent.
With respect to these and other [ 2] limitations of the present study and the continuous RRT benefits shown in a recent meta-analysis [ 3], adequately powered studies comparing SLED and continuous venovenous hemodiafiltration are still urgently needed.
CR was only found to benefit physical function in a recent randomised controlled trial of an 18-session program which compared CR with usual care [ 61].
In addition, G.M. would benefit by a recent increase in one of the state's income tax credits.
Instead they're partners in the production of goods and services in this country and are entitled to a fair share of the system's benefits, Scanlon wrote in a recent article.
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