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The aim of this study was to test the hypothesis that patients with atherosclerotic cardiovascular (CV) disease optimally treated on a statin but with residual atherogenic dyslipidemia (low high-density lipoprotein cholesterol [HDL-C] and high triglycerides) will benefit from addition of niacin with fewer CV events compared with placebo.
These data suggest that clinical benefit from addition of cetuximab to FOLFOX is limited to patients with WT KRAS.
The Panel recognised that patients whose tumours contained high levels of ER derived less benefit from addition of chemotherapy to endocrine therapy.
This suggests that there is a cohort of NSCLC patients who will benefit from addition of an HDAC inhibitor to platinum-based chemotherapy.
Moreover, baseline CEA, TIMP or CRP levels are not associated with differences in benefit from addition of cediranib in Horizon II (Spencer et al, 2013).
Further studies to identify patients in whom this effect is significant could be useful to predict those who are more likely to benefit from addition of anti-cytokine agents to MTX.
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The Zamboney trial was a randomized placebo-controlled study designed to assess whether patients with bone predominant metastatic breast cancer benefited from addition of the VEGF receptor (VEGFR) targeting agent, vandetanib, to endocrine therapy with fulvestrant.
However, a slightly lower charge plateau and higher discharge plateau are obvious for NCA/CNT composite, indicating a smaller polarization of the electrode benefiting from addition of the highly conductive CNTs.
In addition, the benefits from addition of radiation therapy or chemo-radiation therapy following surgical treatment were not evaluated precisely in our analysis, since reviewed papers did not provide information about radiation dose, technique, fractionation or chemotherapy (Fig. 2D).
And the industry stands to benefit from the addition of tens of millions of Americans to the ranks of the insured, under a health care overhaul.
Furthermore, with a recurrence rate so low, it is certain that patients with a low Recurrence Score result will not derive additional benefit from the addition of chemotherapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com