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While PPIs can benefit a subset of patients, off-label usage, coupled with inadequate reassessment of need for continued use, leads to prolonged reduction of stomach acid.
These findings suggest that chemotherapy ± radiotherapy treatment may benefit a subset of patients.
This finding suggests that acute inhalation of hypertonic saline may benefit a subset of children with low MCC values.
We demonstrate that this therapy is likely to benefit a subset of patients whose tumour genetics determine the responsiveness to therapy.
New trial approaches are urgently needed especially for the development of targeted cancer therapies that will only benefit a subset of patients.
Based on the preclinical data, these therapies may benefit a subset of patients with the t(4 14) translocation, particularly those with increased expression of FGFR3 and absence of NRAS mutations.
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The importance of invader-driven catastrophe for conservation issues has distracted attention from the possibility that invasion benefits a subset of native taxa (King et al. 2006; Hagman and Shine 2007).
The low value of cancer medicines is largely driven by two factors: (1) the low average benefit of cancer medicines because they benefit only a subset of the population, and (2) the high cost of oncology drug development due to its high failure rate and the need for large pivotal trials to detect small average benefits.
Finally, two small open label trials of VPA in human subjects have reported modest strength or functional benefit in a subset of those patients [30], [31].
Patient benefit is a subset of cost-effectiveness.
Enzyme replacement therapy (ERT) with alglucosidase alfa has resulted in a clinical benefit in a subset of patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com